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This medicine is a white, round, scored tablet imprinted with “M 100”. and is manufactured by West-Ward Pharmaceutical Corp, a subsidiary of Hikma.

Morphine sulfate 630mg is a prescription drug used to treat moderate to severe acute or chronic pain. It’s sold under several brand names, including Roxanol, Kadian, and Avinza.
Morphine sulfate 60mg  belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.

What form(s) does this medication come in?

Morphine is available in several different forms, including capsules, extended-release capsules, oral solutions, and injections. Take the medication only as directed.

How to use

Take this drug with or without food, usually once daily (every 24 hours). If you have nausea, it may help to take this drug with food.

The dose of long-acting morphine varies widely, based on need. Tablets or capsules are to be taken every 12 or 24 hours on a regular schedule in order to achieve and maintain pain relief.

To preserve the long-acting activity of the medication, the tablets or capsules must not be chewed or crushed.
Over time, this medication may produce tolerance and physical dependence as your body becomes used to the medication. Tolerance occurs when a dose that used to provide acceptable pain relief is no longer effective, and higher doses are required to achieve the same level of pain relief. Physical dependence is a state where the body will go into withdrawal if the medication is stopped suddenly.

Side effects

Morphine may cause severe low blood pressure in people who have low blood volume, anemia, or who were given general anesthetics or phenothiazines.

If you have a head injury or increased intracranial pressure, taking morphine may exaggerate the drug’s respiratory depressant effects. It may also further increase intracranial pressure.

Using morphine when you have bile or pancreatic duct diseases may cause sphincter spasms and reduce biliary and pancreatic secretions.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Common Side Effects of Morphine
The most common side effects of morphine include:

Constipation
Nausea and vomiting
Drowsiness and sedation
Lightheadedness and dizziness
Sweating

Interactions

Morphine may interact with:

CNS depressants
Muscle relaxants
Cimetidine (Tagamet)
Monoamine oxidase inhibitors (MAOIs)
Anticholinergics
P-Glycoprotein (PGP) inhibitors
Diuretics

Drinking alcohol while taking morphine increases your risk of developing life-threatening health problems.

This is especially true if you’re taking extended-release capsules such as Avinza, because alcohol can cause the morphine to be released too quickly. Biting or chewing these capsules, or regular capsules, can also deliver too much morphine at once.

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